When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum. ABSTRACT. We describe an unusual cluster of Corynebacterium striatum infections in 21 patients with chronic obstructive pulmonary disease (COPD) admitted. Objective: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. Methods: A.

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One of the most serious problems related to treatment of the infections caused by C.

Relationship between mutations in the gyrA gene and quinolone resistance in clinical isolates of Corynebacterium striatum and Corynebacterium amycolatum. Patient-to-patient spread of a single strain of Corynebacterium striatum causing infections in a surgical intensive care unit.

Three strains had a mutation at amino acid codon Ser that changes this amino acid for Tyr or Phe. The higher level of moxifloxacin resistance in our strains suggest the existence of a resistance mechanism additional corynrbacterium mutations in gyrA. Expression of functionally active human epidermal growth factor has been brought about in C. However, the patient died on day 73 of admission.

Effects of infection include granulomatous lymphadenopathypneumonitispharyngitisskin infections, and endocarditis.


Based on studies of 16S- rRNAthey have been grouped into the subdivision of gram-positive eubacteria with high G: We obtained XbaI macro-restriction patterns of the 63 C.

Case Reports in Infectious Diseases.

Case Reports in Infectious Diseases

Bergey’s Manual of Systematic Bacteriology. Discussion One of the most serious problems related to treatment of the infections caused by C. High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. Van Hoek AH, et al.

Corynebacterium – Wikipedia

Bdellovibrionales Desulfarculales Desulfobacterales Desulfovibrionales Desulfurellales Desulfuromonadales Myxococcales Syntrophobacterales Syntrophorhabdales. Ten out of 20 carried erm X plus the erm B gene. Resistance to fluoroquinolones in Corynebacterium spp.

Corynebacterium diphtheriae Diphtheria Corynebacterium minutissimum Erythrasma Corynebacterium jeikeium Group JK corynebacterium sepsis. The majority of cases of C. They are widely distributed in nature in the microbiota of animals including the human microbiota and are mostly innocuous, most commonly existing in commensal relationships with their hosts. Isolates were classified as resistant, intermediate, or susceptible, according to criteria defined by CLSI Another cluster has been proposed, consisting of C.

Additionally, 16 conserved signature proteins, which are uniquely found in Corynebacterium species, have been identified. In addition, there is a report of a patient who underwent hemodialysis and corynbeacterium sepsis caused by a Corynebacterium sp. Appropriate susceptibility tests and interpretive criteria are critically needed, in light of the growing emergence of multidrug resistance and its involvement in nosocomial infections.


Diagnostic Microbiology and Infectious Disease.

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Written informed consent was obtained from each patient from whom samples were taken. Exposure to fluoroquinolones selects for spontaneous mutants in large bacterial populations, including those that colonize the skin and mucous membranes such as corynebacteria.

It progressed to disseminated intravascular coagulation and disturbance of consciousness on day 67 of admission. Nondiphtherial corynebacteria have been frequently dismissed as a contaminant when isolated from clinical materials.

Thermodesulfobacteria thermophiles Aquificae Thermotogae Cyanobacteria. International Journal of Cosmetic Science.

Corynebacterium striatum: a diphtheroid with pathogenic potential.

Campanile F, et al. Antimicrobial susceptibilities were determined by micro-dilution in cation adjusted Muller-Hinton broth and interpreted following Clinical and Laboratory Standards Institute CLSI guidelines The ampC gene was detected corynebqcterium 22 of the 28 cefotaxime-resistant C.

Daptomycin has also been proven to be active against C.